In the past two years, space life sciences research in China is characterized by a tendency toward integration of scientific and engineering resources in preparing and implementing advanced space programs. In the field of operational medicine, we carried out an international cooperated Head-Down Bed Rest (HDBR) experiment and investigated the effects of Chinese herbs compounds on astronaut's physiological functions. The effect of microgravity and its mechanisms were further studied from the level of physiology and biology. At the same time, state-level platform for ground and space experiment was established.