Volume 38 Issue 6
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Article Navigation >  Chinese Journal of Space Science  > 2018  >  38(6): 891-899
YU Yang, WANG Shengwei, XU Zhaoxian, JIN Mingjie, YANG Shulin. Advances on Molecular and Biological Effects of Mammalian Cells in Microgravity Environment[J]. Chinese Journal of Space Science, 2018, 38(6): 891-899. doi: 10.11728/cjss2018.06.891
Citation: YU Yang, WANG Shengwei, XU Zhaoxian, JIN Mingjie, YANG Shulin. Advances on Molecular and Biological Effects of Mammalian Cells in Microgravity Environment[J]. Chinese Journal of Space Science, 2018, 38(6): 891-899. doi: 10.11728/cjss2018.06.891
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Advances on Molecular and Biological Effects of Mammalian Cells in Microgravity Environment

doi: 10.11728/cjss2018.06.891

  • School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094

  • Received Date: 2017-09-11
  • Rev Recd Date: 2018-04-21
  • Publish Date: 2018-11-15
    Abstract
  • With the continuous development of manned space program, astronaut health problems, such as cardiovascular diseases, immuno-suppression, muscle wasting, and osteoporosis, etc., caused by microgravity have attracted extensive concern, and these astronaut-derived health problems have become a major obstacle to the exploration of space. Many studies have focused on the changes of body and cell in microgravity conditions. Recent studies have shown that cell degradation and changes in the cytoskeleton can be induced by microgravity, and a series of changes caused by microgravity at molecular level were also found. In this paper, the recent studies on the behavior of immune cells, endothelial cells, bone cells and cancer cells in microgravity condition are reviewed. The results can provide instruction and reference for the further study of the disease occurrence in microgravity conditions, and provide some ideas for the treatment of diseases caused by microgravity conditions.

     

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