Volume 40 Issue 4
Jul.  2020
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YANG Chao, XU Zihan, LI Kai, ZHANG Hongyu, WANG Hailong, WU Feng, CAO Hongqing, KAN Guanghan, LI Yinghui, DAI Zhongquan. Inhibitory Effects of Head-down Bed Rest on Bone, Glycolipid Metabolism of Rhesus and Their Correlation Analysis[J]. Journal of Space Science, 2020, 40(4): 540-546. doi: 10.11728/cjss2020.04.540
Citation: YANG Chao, XU Zihan, LI Kai, ZHANG Hongyu, WANG Hailong, WU Feng, CAO Hongqing, KAN Guanghan, LI Yinghui, DAI Zhongquan. Inhibitory Effects of Head-down Bed Rest on Bone, Glycolipid Metabolism of Rhesus and Their Correlation Analysis[J]. Journal of Space Science, 2020, 40(4): 540-546. doi: 10.11728/cjss2020.04.540

Inhibitory Effects of Head-down Bed Rest on Bone, Glycolipid Metabolism of Rhesus and Their Correlation Analysis

doi: 10.11728/cjss2020.04.540
  • Received Date: 2018-03-14
  • Rev Recd Date: 2019-08-22
  • Publish Date: 2020-07-15
  • Bone loss and subclinical diabetes-like are developed during long-term spaceflight. Recently, it was demonstrated that bone was able to regulate energy metabolism and testosterone synthesis via osteocalcin. In this study, we analyzed the changes of bone metabolism and glycolipid metabolism of rhesus and their association (P<0.05). Serum insulin and LDL content significantly decreased at 7 days and remained at a low level, and the blood glucose level showed a significant decline at 7 days, but recovery at 21 days. The correlation analysis showed that there was a correlation between osteocalcin and blood glucose, cortisol and HDL. The experimental results show that there is mutual regulation between bone and glycolipid metabolism in the bedrest experiment of rhesus.

     

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