Volume 41 Issue 2
Mar.  2021
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YANG Chao, XU Zihan, LI Kai, ZHANG Hongyu, WANG Hailong, WU Feng, XU Zi, DAI Zhongquan, LI Yinghui. Effects of 180-day's Isolation on Bone, Glycolipid Metabolism and Their Correlation Analysis[J]. Journal of Space Science, 2021, 41(2): 293-300. doi: 10.11728/cjss2021.02.293
Citation: YANG Chao, XU Zihan, LI Kai, ZHANG Hongyu, WANG Hailong, WU Feng, XU Zi, DAI Zhongquan, LI Yinghui. Effects of 180-day's Isolation on Bone, Glycolipid Metabolism and Their Correlation Analysis[J]. Journal of Space Science, 2021, 41(2): 293-300. doi: 10.11728/cjss2021.02.293

Effects of 180-day's Isolation on Bone, Glycolipid Metabolism and Their Correlation Analysis

doi: 10.11728/cjss2021.02.293
  • Received Date: 2018-03-14
  • Rev Recd Date: 2019-08-22
  • Publish Date: 2021-03-15
  • During the long-term space flight, the astronauts are in the confined weightlessness environment. However, the impact of confined environment on bone metabolism and glucose and lipid metabolism is not elucidated. In this paper, the changes of bone metabolism, glucose and lipid metabolism and their correlations through Space 180 CELSS System test of four volunteers were analyzed. Results showed that confined environment affected bone formation indices (BGP, PICP, BAP). Serum insulin level changed significantly during the test, and Lipid metabolism indicators have a downward trend. Correlation analysis showed that BGP was positively correlated with FRUC (r=0.525, p=0.001). There was also a significant positive correlation between BGP, CHOL and LDL (r=0.376, p=0.024; r=0.391, p=0.018). The results showed that the metabolism of bone and glycolipid was changed obviously in this experiment, and there was mutual regulation between them.

     

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