The ground comprehensive test of spacecraft electronic equipment is an important part in the development of spacecraft. It plays an important role in equipment function verification and performance evaluation. The ground test system of the Chang'E-4 lander load electric control box adopts modular, reusable design and CPU+FPGA single-machine integrated architecture. It can provide power supply test, 1553B communication bus simulation test, indirect command test, asynchronous serial communication test, real-time data processing and other functions in one integrated system, is suitable for spacecraft electronic equipment single machine debugging, configuration test and environmental simulation test and other types of test requirements. The test of each interface, function and performance of the load electric control box indicates that the system meets the test requirements of stand-alone debugging, status confirmation and troubleshooting of the spaceborne equipment, which strongly supports the successful on-orbit operation of the Chang'E-4 lander load electric control box.