Progress Update in Space Cell Mechano-biological Coupling

LONG Mian; SUN Shujin; LI Ning; LÜ Dongyuan; GAO Yuxin

doi:10.11728/cjss2020.05.935

Progress Update in Space Cell Mechano-biological Coupling

doi: 10.11728/cjss2020.05.935

National Microgravity Laboratory, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190

基金项目:

Supported by Strategic Priority Research Program and Frontier Science Key Project of Chinese Academy of Sciences (XDA04020202-17, XDA04020416, XDA15014100 and QYZDJSSW-JSC018), National Natural Science Foundation of China (U1738115)

详细信息

作者简介:
LONG Mian,E-mail:mlong@imech.ac.cn

中图分类号: V524
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出版历程
- 收稿日期: 2020-03-13
- 刊出日期: 2020-09-15

Progress Update in Space Cell Mechano-biological Coupling

National Microgravity Laboratory, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190

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Author Bio:
LONG Mian,E-mail:mlong@imech.ac.cn

摘要

摘要: Recent progresses in 2018-2019 from space experiments onboard SJ-10 recoverable satellite and on parabolic flight were summarized, mainly focusing on cell mechano-biological coupling under microgravity. In the meantime, technical pre-research and experimental system design for the biomechanics research platform on China Space Station was carried out and updated.
- Microgravity /
- SJ-10 satellite /
- Parabolic flight /
- Endothelial cells /
- Mesenchymal stem cells /
- Hepatocytes /
- Mechanotransduction /
- China Space Station
Abstract: Recent progresses in 2018-2019 from space experiments onboard SJ-10 recoverable satellite and on parabolic flight were summarized, mainly focusing on cell mechano-biological coupling under microgravity. In the meantime, technical pre-research and experimental system design for the biomechanics research platform on China Space Station was carried out and updated.
- Microgravity /
- SJ-10 satellite /
- Parabolic flight /
- Endothelial cells /
- Mesenchymal stem cells /
- Hepatocytes /
- Mechanotransduction /
- China Space Station

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参考文献(4)

[1]	LÜ Dongyuan, SUN Shujin, ZHANG Fan, et al. Microgravity-induced hepatogenic differentiation of rBMSCs on board SJ-10 satellite[J]. FASEB J., 2019, 33(3):4273-4286
[2]	LI Ning, WANG Chengzhi, SUN Shujin, et al. Microgravity-induced alterations of inflammation-related mechanotransduction in endothelial cells on board SJ-10 satellite[J]. Front. Physiol. 2018, 9:1025
[3]	SUN Shujin, WANG Chengzhi, BI Yuzhen, et al. An integration design of gas exchange, bubble separation and flow control in a space cell culture system on board the SJ-10 satellite[J]. Rev. Sci. Instrum., 2019, 90(7):075114
[4]	MOSER D, SUN Shujin, LI Ning, et al. Cells flow and immune cell priming under alternating g-forces in parabolic flight[J]. Sci. Rep., 2019, 9:11276