Abstract: Cislunar space offers tremendous promise for advancing science, technology and exploration, and it is expected to be a new sphere of human activity in the next ten years. The White House Office of Science and Technology Policy released the first National Cislunar Science and Technology Strategy to realize U.S. leadership in responsible, peaceful, and sustainable exploration and use of Cislunar space, including the Moon, by stakeholders and collaboration across U.S. government agencies as well as international partners and private entities, consistent with the U.S. Space Priorities Framework. The Strategy provides an early common vision and the first science and technology objectives, including support research and development to enable long-term growth in Cislunar space, expand international S & T cooperation in Cislunar space, extend U.S. space situational awareness capabilities into Cislunar space, and implement Cislunar communications and positioning, navigation, and timing capabilities with scalable and interoperable approaches, to foster scientific discovery, economic development, and international cooperation.