Abstract: Polar Mesospheric Clouds (PMCs), as ice crystal clouds formed in the middle and upper atmosphere (approximately 83 km), have a seasonal onset that serves as an important parameter for studying the coupling processes between thermodynamics and dynamics in the polar mesosphere. This paper, based on multi-source observational data from 1979 to 2023, systematically analyzes the long-term evolution characteristics of the onset of PMCs in both hemispheres and examines its correlations with the reversal time of stratospheric zonal mean wind and solar activity. The results show that there are significant differences in the onset of PMCs between the two hemispheres: the interannual variation (with a standard deviation of 22 days) in the southern hemisphere is about twice that in the northern hemisphere (11 days), which may be related to differences in thermal and dynamic processes such as inter-hemispheric circulation modes and the intensity of gravity wave activity. In the southern hemisphere, the onset of PMCs season exhibits a very strong positive correlation with the reversal time of the stratospheric zonal mean wind, while in the northern hemisphere, although a negative correlation is observed, the approximately 60-day difference does not directly indicate a causal relationship between the two. The regulation of the onset by solar activity (Lyman-α radiation) also shows hemispheric asymmetry. In the northern hemisphere, there was a certain negative correlation with solar activity before 2011 that later weakened due to changes in the stratospheric dynamic background, whereas the southern hemisphere exhibited only a weak response. This indicates that both solar radiation effects and dynamic processes may jointly contribute. In addition, the discrepancies among multi-source data suggest that differences in detection systems and data types can introduce uncertainties in studies of the long-term variation characteristics of PMCs.