Abstract: In intersecting areas of terrestrial radio services and space radio services, there is currently no well-established model for quantifying the interference of Satellite-to-Ground reverse communication link. This study investigates the physical parameters and algorithms of ITU-R P.452 and P.2001 propagation models to develop a methodology integrating with SRTM3 digital elevation model for evaluate the interference in the frequency range of Satellite-to-Ground reverse communication link. Through a comparative evaluation of ITU Study Group 3 measurement data against predicted data from two models across five globally representative regions, this study identifies appropriate radio propagation models in different scenarios. The methodology that P.452 model integrating SRTM3 provides references for investigation of in-orbit interference and frequency compatibility assessment on Satellite-to-Ground reverse communication link.