X-ray pulsars navigation is a new celestial navigation method, the principle of which is steady, credible and free from the limits of the near earth space. But its navigation precision is poor whyen it is used in orbital maneuver. For this problem, X-ray pulsars navigation/SINS integrated navigation system is proposed and testified by simulation in this paper. Results shows that the navigation precision of this new navigation system is preferable even during the orbital maneuver, and the drift of navigation error of SINS is well controlled. The new navigation system extends the application of X-ray pulsars navigation and lays a theory foundation to the engineering realization of X-ray pulsars navigation.