2018, 38(6): 891-899.
doi: 10.11728/cjss2018.06.891
Abstract:
With the continuous development of manned space program, astronaut health problems, such as cardiovascular diseases, immuno-suppression, muscle wasting, and osteoporosis, etc., caused by microgravity have attracted extensive concern, and these astronaut-derived health problems have become a major obstacle to the exploration of space. Many studies have focused on the changes of body and cell in microgravity conditions. Recent studies have shown that cell degradation and changes in the cytoskeleton can be induced by microgravity, and a series of changes caused by microgravity at molecular level were also found. In this paper, the recent studies on the behavior of immune cells, endothelial cells, bone cells and cancer cells in microgravity condition are reviewed. The results can provide instruction and reference for the further study of the disease occurrence in microgravity conditions, and provide some ideas for the treatment of diseases caused by microgravity conditions.